Amniotic membrane and amniotic cells: Potential therapeutic tools to combat tissue inflammation and fibrosis?
Placenta. 2011 Oct;32 Suppl 4:S320-5. doi: 10.1016/j.placenta.2011.04.010. Epub 2011 May 12.
Manuelpillai U1, Moodley Y, Borlongan CV, Parolini O. 1Monash Institute of Medical Research, Monash University, Clayton, Victoria 3168, Australia.
Abstract In addition to the placenta, umbilical cord and amniotic fluid, the amniotic membrane is emerging as an immensely valuable and easily accessible source of stem and progenitor cells. This concise review will focus on the stem/progenitor cell properties of human amniotic epithelial and mesenchymal stromal cells and evaluate the effects exerted by these cells and the amniotic membrane on tissue inflammation and fibrosis.
Copyright © 2011 Elsevier Ltd. All rights reserved. PMID: 21570115 [PubMed – indexed for MEDLINE]