{"id":7967,"date":"2010-03-01T00:00:08","date_gmt":"2010-03-01T00:00:08","guid":{"rendered":"http:\/\/cellgenuity.com\/?p=7967"},"modified":"2018-06-28T17:10:56","modified_gmt":"2018-06-28T17:10:56","slug":"repair-of-oronasal-fistulas-with-human-amniotic-membrane-in-minipigs","status":"publish","type":"post","link":"https:\/\/cellgenuity.com\/index.php\/2010\/03\/01\/repair-of-oronasal-fistulas-with-human-amniotic-membrane-in-minipigs\/","title":{"rendered":"Repair of oronasal fistulas with human amniotic membrane in minipigs"},"content":{"rendered":"<div id=\"block-yui_3_17_2_6_1510095114584_173882\" class=\"sqs-block markdown-block sqs-block-markdown\" data-block-type=\"44\">\n<div class=\"sqs-block-content\">\n<p><strong>Repair of oronasal fistulas with human amniotic membrane in minipigs\u00a0<\/strong><\/p>\n<p><a href=\"http:\/\/cellgenuity.com\/wp-content\/uploads\/2018\/05\/repair-of-oronasal-fistulas-with-human-amniotic-membrane-in-minipigs.pdf\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-thumbnail wp-image-8031\" src=\"http:\/\/cellgenuity.com\/wp-content\/uploads\/2018\/05\/cellgenuitydownloadlogo-150x150.png\" alt=\"\" width=\"150\" height=\"150\" \/><\/a><\/p>\n<\/div>\n<\/div>\n<div id=\"block-yui_3_17_2_6_1510095114584_173944\" class=\"sqs-block html-block sqs-block-html\" data-block-type=\"2\">\n<div class=\"sqs-block-content\">\n<p>Br J Oral Maxillofac Surg. 2010 Mar;48(2):131-5. doi: 10.1016\/j.bjoms.2009.04.025. Epub 2009 May 23.<\/p>\n<p>Kesting MR1, Loeffelbein DJ, Classen M, Slotta-Huspenina J, Hasler RJ, Jacobsen F, Kreutzer K, Al-Benna S, Wolff KD, Steinstraesser L.<br \/>\n1Department of Oral and Maxillofacial Surgery, Technische Universit\u00e4t M\u00fcnchen, Ismaninger Str. 22, D-81675 M\u00fcnchen, Germany.<\/p>\n<p><strong>Abstract<\/strong><br \/>\nWe evaluated the use of multilayer human amniotic membrane (HAM) as a grafting material for the repair of mid-palate oronasal fistulas in seven Berlin minipigs. After two weeks, three animals had the fistulas repaired with multilayered HAM grafts, three had them repaired with a collagen-based dermal substitute (INTEGRA((R)), Integra Life Sciences, Plainsboro, NJ, USA), and one fistula was left untreated to serve as a control. Grafts were interposed between the oral and nasal mucosa, traversing the fistulas. After healing for 40 days, the pigs were killed for clinical, histological, and immunohistochemical examination. Two of the three fistulas closed with HAM were successful, the diameter of the third was reduced in size, and there was no change in the diameter of the fistula in the control. This study shows successful closure of oronasal fistulas in minipigs using interposed grafts of cryopreserved HAM, and offers promise as a simple and effective technique for tension-free closure of such fistulas.<\/p>\n<p>PMID: 19477056 [PubMed \u2013 indexed for MEDLINE]\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Repair of oronasal fistulas with human amniotic membrane in minipigs\u00a0 Br J Oral Maxillofac Surg. 2010 Mar;48(2):131-5. doi: 10.1016\/j.bjoms.2009.04.025. Epub 2009 May 23. Kesting MR1, Loeffelbein DJ, Classen M, Slotta-Huspenina J, Hasler RJ, Jacobsen F, Kreutzer K, Al-Benna S, Wolff KD, Steinstraesser L. 1Department of Oral and Maxillofacial Surgery, Technische Universit\u00e4t M\u00fcnchen, Ismaninger Str. 22, [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pgc_meta":"","footnotes":""},"categories":[70,23,83,22,82],"tags":[],"class_list":["post-7967","post","type-post","status-publish","format-standard","hentry","category-human-amniotic-membrane","category-maxillofacial","category-minipigs","category-oral","category-oronasal-fistulas"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Repair of oronasal fistulas with human amniotic membrane in minipigs - CellGenuity | Welcome to CellGenuity<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cellgenuity.com\/index.php\/2010\/03\/01\/repair-of-oronasal-fistulas-with-human-amniotic-membrane-in-minipigs\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Repair of oronasal fistulas with human amniotic membrane in minipigs - CellGenuity | Welcome to CellGenuity\" \/>\n<meta property=\"og:description\" content=\"Repair of oronasal fistulas with human amniotic membrane in minipigs\u00a0 Br J Oral Maxillofac Surg. 2010 Mar;48(2):131-5. doi: 10.1016\/j.bjoms.2009.04.025. 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